CD34 Rabbit Monoclonal Antibody(ARB904)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
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Brand:
CAT.NO. : ARB6696
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Product Details
Background
CD23 antigen is a transmembrane glycoprotein by various hematopoietic cell types and functions as a low-affinity receptor for IgE. CD23 is involved in regulating IgE production and has other potential biologic functions, including promoting the survival of germinal center B lymphocytes.
CD23 is found in some mature B-cell lymphomas and in Reed-Sternberg cells in Hodgkin disease. Follicular dendritic cells and some activated B-cells within germinal centers express CD23 in high density and mantle zone B-cells are stained weakly. The majority of chronic lymphocytic leukemias/small lymphocytic lymphomas are CD23 positive, whereas mantle cell lymphomas are generally negative.
CD23 has been shown to be useful for the differentiation of small lymphocytic lymphomas and mantle cell lymphoma.
CD23 is found in some mature B-cell lymphomas and in Reed-Sternberg cells in Hodgkin disease. Follicular dendritic cells and some activated B-cells within germinal centers express CD23 in high density and mantle zone B-cells are stained weakly. The majority of chronic lymphocytic leukemias/small lymphocytic lymphomas are CD23 positive, whereas mantle cell lymphomas are generally negative.
CD23 has been shown to be useful for the differentiation of small lymphocytic lymphomas and mantle cell lymphoma.
Overview
| Target | CD34 |
| Host Species | rabbit monoclonal antibody |
| Molecular Weight | 41 kDa |
| Purity | ProA affinity purified IgG |
| Species Cross-reactivity | Human |
| Form | Liquid |
| Applications | IHC-P |
| Swissprot ID | P28906 |
| Immunogen | Synthetic peptide corresponding to CD34 residues within aa285-385 of CD34 |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
| Storage Conditions | -25°C to -18°C |
| Dilutions | IHC-P: 1:100-1:200 |
| Subcellular Location | Membrane |
| Recommended Method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes |
data
Immunohistochemical staining of human placenta tissue sections using CD34 Rabbit Monoclonal Antibody (ARB904).
Immunohistochemical staining of human kidney tissue sections using CD34 Rabbit Monoclonal Antibody (ARB904).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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