CD38 Rabbit Monoclonal Antibody(ARB906)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
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Brand:
CAT.NO. : ARB6698
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Product Details
Background
CD38, also known as ADP-ribosyl cyclase, synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. CD38 also has cADPr hydrolase activity. It is found on immature cells of the B and T cell lineages but not on most mature resting peripheral lymphocytes. It is also present on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, Ig-secreting plasma cells, monocytes, NK cells, erythroid and myeloid progenitors in the bone marrow and brain cells. CD38 is uesd to identify plasma cells and plasmablastic differentiation, and evaluate the prognosis for B-cell chronic lymphocytic leukemia (CLL) patients.
Overview
| Target | CD38 |
| Host Species | rabbit monoclonal antibody |
| Molecular Weight | 34 kDa |
| Purity | ProA affinity purified IgG |
| Species Cross-reactivity | Human |
| Form | Liquid |
| Applications | IHC-P |
| Swissprot ID | P28907 |
| Immunogen | Synthetic peptide corresponding to residues within aa200-300 of CD38 |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
| Storage Conditions | -25°C to -18°C |
| Dilutions | IHC-P: 1:100-1:200 |
| Subcellular Location | Membrane |
| Recommended Method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes |
data
Immunohistochemical staining of human appendix tissue sections using CD38 Rabbit Monoclonal Antibody (ARB906).
Immunohistochemical staining of human tonsil tissue sections using CD38 Rabbit Monoclonal Antibody (ARB906).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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