CD38 Rabbit Monoclonal Antibody(ARM607)
Key features and details
- Target:
- Clone ID:
- Host:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6898
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Size:
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Product Details
Background
Cluster of Differentiation 38 (CD38) is an ontogenesis marker in T-cells which is also expressed in erythrocytes, platelets, prostate epithelial cells, islet cells, smooth and striated muscle cells, renal tubules, and retinal ganglial cells. CD38(+) stained B-cells are mainly present in germinal centers of secondary lymphoid organs, while the marginal zone is usually negative. A panel of CD38, CD138, MUM1, and EMA is very useful for the diagnosis of immunodeficiency-related lymphoma, such as plasmablastic lymphoma, primary effusion lymphoma, and large B-cell lymphoma in Castleman’s disease. Recent research has found a panel of CD38, CD44, and TCL-1 to be useful in recognizing large B-cell lymphoma with c-Myc gene rearrangement, making it important in differential diagnoses of diffuse large B-cell lymphoma, Burkitt’s lymphoma, and B-cell lymphoma.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Molecular Weight |
13,788 Da |
|
3D Structure |
ModBase 3D Structure for P28907 |
|
Isotype |
IgG |
|
Host |
Rabbit |
|
Species Reactivity |
Human |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human tonsil tissue using CD38 Rabbit Monoclonal Antibody (ARM607).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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