CD43 Mouse Monoclonal Antibody(ARM949)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6739
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Cluster of Differentiation 43 (CD43), also known as Sialophorin, is a transmembrane protein that plays a role in T-cell activation. CD43 is normally expressed abundantly on the surface of differentiated hematopoietic stem cells, including monocytes, granulocytes, T-lymphocytes, and some B-lymphocytes. Due to the efficacy of CD43 immunohistochemical staining in granulocytes, it is an effective marker for myeloid tumours, while other antibodies demonstrate weak staining under these conditions. Given the low reactivity of Anti-CD43 with B-cells, positive staining of CD43 is implicated in a number of lymphoid and myeloid tumours, with over 90% positive staining in T-cell lymphomas. When CD43 is used in combination with CD45 and L26, immunotyping of various lymphomas can be obtained; this is particularly true when co staining a lymphoid infiltrate with CD20 and CD3.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Molecular Weight |
40,322 Da |
|
3D Structure |
ModBase 3D Structure for P16150 |
|
Isotype |
IgG1 |
|
Host |
Mouse |
|
Species Reactivity |
Human |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human tonsil tissue using CD43 Mouse Monoclonal Antibody (ARM949).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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