CD63 Rabbit Monoclonal Antibody(ARA960)
Key features and details
- Reactivity:Human
- Application:WB, IHC-P
- Host:Rabbit
- Clonality:Monoclonal
- lsotype:IgG
- Target:CD63
-
Brand:
CAT.NO. : ARA6812
RMB Please choose
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
CD63 antigen is a protein that, in humans, is encoded by the CD63 gene. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak Syndrome . Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene. Alternative splicing results in multiple transcript variants encoding different proteins.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:200 - 1:1000 |
Overview
|
Antibody Type |
Recombinant Rabbit monoclonal Antibody |
|
Immunogen |
Recombinant protein within Human CD63 aa 103-203. |
|
Species Reactivity |
Human |
|
Validated Applications |
WB, IF-Cell, FC, IR, IHC-P |
|
Molecular Weight |
Predicted band size: 26 kDa |
|
Positive Control |
SK-MEL-28 cell lysate, U-87 MG cell lysate, HUVEC cell lysate, K-562 cell lysate, HEK-293 cell lysate, HL-60 cell lysate, K-562, human melanoma tissue. |
|
Conjugation |
unconjugated |
|
Form |
Liquid |
|
Storage Buffer |
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide |
|
Isotype |
IgG |
|
Purification Method |
Protein A affinity purified |
Data
Immunohistochemical staining of human melanoma tissue using CD63 Rabbit Monoclonal Antibody(ARA960)
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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