CD68 Rabbit Monoclonal Antibody(ARB830)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
-
Brand:
CAT.NO. : ARB6620
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。
Product Details
Background
CD68 is a highly glycosylated transmembrane protein which is mainly located in lysosomes. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions.CD68 is detected in different types of macrophages of monocyte lineage and also reacts with myeloid precursor cells in the bone marrow. Positivity is seen in Kupffer cells and histiocytes in normal lymphoid tissue, but also mast cells and microglia. In tumor tissues, it is detected in fibrous-histiocytic tumors, some epithelial neoplasms, epithelioid cells of some malignant melanomas.CD68 may be useful for the identification of myelomonocytic and histiocytic tumors.
Overview
| Target | CD68 |
| Host Species | rabbit monoclonal antibody |
| Molecular Weight | 37 kDa |
| Purity | ProA affinity purified IgG |
| Species Cross-reactivity | Human |
| Form | Liquid |
| Applications | IHC-P |
| Swissprot ID | P34810 |
| Immunogen | Synthetic peptide corresponding to CD68 residues within aa100-200 of CD68 |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
| Storage Conditions | -25°C to -18°C |
| Dilutions | IHC-P: 1:100-1:200 |
| Subcellular Location | Membrane |
| Recommended Method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes |
Data
Immunohistochemical staining of human splenic tissue sections was performed using CD68 Rabbit Monoclonal Antibody (ARB830).
Immunohistochemical staining of human tonsillar tissue sections was performed using CD68 Rabbit Monoclonal Antibody (ARB830).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
New Products
