CD79a Rabbit Monoclonal Antibody(ARA771)
Key features and details
- Target:
- Clone ID:
- Host:
- Clone Type:
- Purity:
- Species Cross-reactivity:
- Applications:
- Isotype:
-
Brand:
CAT.NO. : ARA6558
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
Product Details
Background
Cluster of differentiation CD79a also known as B-cell antigen receptor complex-associated protein alpha chain is a protein that in humans is encoded by the CD79A gene. The CD79a protein together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR), and plays multiple and diverse roles in B cell development and function. CD79a protein is expressed in virtually all mature and immature B cells and the majority of B-cell neoplasms, including precursor B–acute lymphocytic leukemia (pre-B–ALL), L and H lymphocyte predominance Hodgkin’s lymphoma, and many plasma cell tumors. Therefore, antibodies to CD79a are useful in the differential diagnosis of B-cell neoplasms from T-cell neoplasms or myeloid neoplasms, or L and H lymphocyte predominance Hodgkin’s lymphoma from classic Hodgkin’s lymphoma. In addition, CD79a is a useful marker in the diagnosis of precursor B–acute lymphoblastic leukemia (pre-B–ALL) because many of these tumors are negative for other B-cell markers, such as CD20 and CD45RA.
Application
|
Application |
Dilution Ratio |
|
WB |
1:500-1:1,000 |
|
IHC-P |
1:6,400-1:12,800 |
|
FC |
1:800-1:2,000 |
Overview
|
Host Species |
Rabbit |
|
Species Cross-reactivity |
Human |
|
Application |
WB, IHC-P, FC |
|
Immunogen |
A synthetic peptide corresponding to the N-term of CD79a |
|
Purity |
ProA affinity purified IgG |
|
Clone Type |
Recombinant Monoclonal |
|
Isotype |
IgG |
|
Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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