CDH17 Rabbit Monoclonal Antibody(ARB917)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
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Brand:
CAT.NO. : ARB6709
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Size:
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Product Details
Background
CDH17 may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. CDH17 expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. CDH17 is a highly specific marker in colon cancer and is a more sensitive marker than CDX2 and CK20. Overexpression of CDH17 correlates to poor prognosis in patients with epithelial ovarian cancer. CDH17 may be helpful for early diagnosis of Barrett’s esophagus. CDH17 has been shown to be a useful marker for distinguishing between primary urinary bladder adenocarcinoma and urothelial carcinoma with glandular differentiation.
Application
| Application | Dilution Ratio |
|---|---|
| IHC | 1:100-1:200 |
Overview
| Predicted Molecular Wt | 92kDa |
| Species Cross-reactivity | Human |
| Applications | IHC-P |
| Purity | ProA affinity purified IgG |
| Form | Liquid |
| Swissprot ID | Q12864 |
| Subcellular location | Membrane |
| Recommended Method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes. |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. |
Data
Immunohistochemical staining of human colon tissue using CDH17 Rabbit Monoclonal Antibody (ARB917).
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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