Chromogranin A Mouse Monoclonal Antibody(ARM889)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
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Brand:
CAT.NO. : ARM6679
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Size:
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Product Details
Background
Chromogranin A is localized in secretory granules of neurons and endocrine cells in tissues, including pituitary, adrenal medulla, thyroid, pancreatic islets, and the gastrointestinal tract. Neuroendocrine cells exhibit a fine granular immunoreactivity to Anti-Chromogranin A. It is widely recognized that co-expression of keratins and chromogranin A implies a neuroendocrine lineage. High expression of chromogranin A and negative staining with Anti-Keratin is a possible indication of paraganglioma. Positive staining for chromogranin A and neuron-specific enolase is representative of neuroendocrine neoplasms. Many pituitary adenomas and prolactinomas stain positively for chromogranin A.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Molecular Weight |
50,688 Da |
|
Chromosome Location |
Chromosome: 14; NC_000014.8 (93389445..93401638). Location: 14q32 |
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3D Structure |
ModBase 3D Structure for P10645 |
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Isotype |
IgG1 |
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Host |
Mouse |
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Species Reactivity |
Human |
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Purity/Purification |
Purified |
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Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
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Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human appendix tissue using Chromogranin A Mouse Monoclonal Antibody (ARM889).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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