COL4A5 Rabbit Monoclonal Antibody(ARB928)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
-
Brand:
CAT.NO. : ARB6720
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Deletions covering the N-terminal regions of COL4A5 and COL4A6, which are localized in a head-to-head manner, are found in the chromosome Xq22.3 centromeric deletion syndrome. This results in a phenotype with features of diffuse leiomyomatosis and Alport syndrome (DL-ATS).
Application
| Application | Dilution Ratio |
|---|---|
| IHC | 1:100-1:200 |
Overview
| Predicted Molecular Wt | 161kDa |
| Species Cross-reactivity | Human |
| Applications | IHC-P |
| Purity | ProA affinity purified IgG |
| Form | Liquid |
| Swissprot ID | P29400 |
| Subcellular location | Basement membrane |
| Recommended method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes. |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. |
Data
Immunohistochemical staining of human kidney tissue using COL4A5 Rabbit Monoclonal Antibody (ARB928).
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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