CYP11B2 Rabbit Polyclonal Antibody
Key features and details
- Reactivity:Human
- Application:IHC
- Host:Rabbit
- Clonality:Polyclonal
- Target:CYP11B2
-
Brand:
CAT.NO. : ARA6792
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Size:
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Product Details
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:50-1:300 |
Overview
|
Clonality |
Polyclonal |
|
Isotype |
IgG |
|
Immunogen |
Synthetic peptide of human CYP11B2 |
|
Abbre |
CYP11B2 |
|
Synonyms |
mitochondrial, ALDOS, Aldosterone synthase, Aldosterone-synthesizing enzyme, C11B2, CYP11B2, CYPXIB2, Cytochrome P-450Aldo, Cytochrome P-450C18, Cytochrome P450 11B2, P-450Aldo, P-450C18, Steroid 18-hydroxylase, mitochondrial |
|
Swissprot |
P19099 |
|
Calculated MW |
58 kDa |
|
Observed MW |
Refer to figures |
|
Cellular Localization |
Mitochondrion membrane |
|
Concentration |
1 mg/mL |
|
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH 7.4 |
|
Purification Method |
Antigen affinity purification |
Data
Immunohistochemical staining of human brain tissue sections using CYP11B2 Rabbit Polyclonal Antibody.
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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