Cytochrome P450 7A1 Rabbit Polyclonal Antibody
Key features and details
- Reactivity:Human
- Application:WB
- Host:Rabbit
- Clonality:Polyclonal
- Target:Cytochrome P450 7A1
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Brand:
CAT.NO. : ARA6805
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Product Details
Background
CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.
Application
|
Application |
Dilution Ratio |
|
WB |
1:500 - 1:1000 |
Overview
|
Immunogen |
Recombinant fusion protein of human Cytochrome P450 7A1. The exact sequence is proprietary |
|
Purification Method |
The antibody was purified by immunogen affinity chromatography |
|
Clonality |
Polyclonal |
|
Form |
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide |
|
Gene Name |
CYP7A1 |
|
Synonyms |
CYP7; Cholesterol 7-alpha-monooxygenase; CYPVII; Cholesterol 7-alpha-hydroxylase; Cytochrome P450 7A1 |
|
Gene ID (Human) |
1581 |
|
Gene ID (Mouse) |
13122 |
|
Gene ID (Rat) |
25428 |
|
Protein ID (Human) |
P22680 |
|
Protein ID (Mouse) |
Q64505 |
|
Protein ID (Rat) |
P18125 |
Data
Western blot analysis of Cytochrome P450 7A1 expression in HepG2 (A) whole cell lysates. (Predicted band size: 57 kD; Observed band size: 58 kD)
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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