Cytokeratin 8/18 Rabbit/Mouse Monoclonal Antibody(ARM891)

Key features and details

  • Target: Cytokeratin 8/18
  • Clone ID: ARM891
  • Host Species: Rabbit/Mouse
  • Species Cross-reactivity: Human
  • Applications: IHC-P
  • Dilution: 1:50-1:200
  • Clonality: Monoclonal
  • Brand:
CAT.NO. : ARM6681
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Size:
1mL
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Product Details
Background
Cytokeratin 8 & 18 are present in various epithelia including that of the breast, thyroid, respiratory tract, and gastrointestinal tract. Anti-Cytokeratin 8 & 18 stains adenocarcinomas and most non-keratinizing squamous carcinomas, but does not stain keratinizing squamous carcinomas. Since Cytokeratin 18 is scarce in normal epidermis, Anti-Cytokeratin 8 & 18 is used to detect Paget cells in such samples. Cytokeratin 8 & 18 helps identify colorectal carcinoma metastases as it is more sensitive than genetic tests.
Application

Application

Dilution Ratio

IHC

1:50 - 1:200

Overview

Isotype

Rabbit IgG+Mouse IgG1

Host

Rabbit, Mouse

Species Reactivity

Human

Specificity

Cytokeratin 8/18

Purity/Purification

Purified

Form/Format

Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide

Immunogen

Cocktail

Data


Immunohistochemical staining of human colon tissue using Cytokeratin 8/18 Rabbit/Mouse Monoclonal Antibody (ARM891).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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