Cytokeratin 8 Rabbit Monoclonal Antibody(ARA739)
CAT.NO. : ARA6526
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
Background
Cytokeratin 8 (CK8) is a member of the type II intermediate filament (IF) gene family, the majority of the cellular CK8 is assembled with its partner, CK18, into highly insoluble 10 nm filaments that extend from the nucleus to the internal leaflet of the plasma membrane.CK8 is always expressed by simple epithelial cells and by some carcinoma cells. In non-cancerous tissue, CK8 commonly expressed in normal glandular epithelia, transitional cell epithelium, and hepatocyte. In cancerous tissue, CK8 high expressed in adenocarcinoma, such as human breast or colorectal carcinoma.
Application
|
Application |
Dilution Ratio |
|
WB |
1:2,500-1:5,000 |
|
IHC-P |
1:100-1:200 |
|
IF/ICC |
1:5,000-1:10,000 |
|
FC |
1:200-1:800 |
|
IP |
1:10-1:30 |
Overview
|
Host Species |
Rabbit |
|
Species Cross-reactivity |
Human |
|
Application |
WB, IHC-P, IF/ICC, FC, IP |
|
Immunogen |
A synthetic peptide corresponding to residues on the C-terminus of human Cytokeratin 8 was used as an immunogen. |
|
Purity |
ProA affinity purified IgG |
|
Clone Type |
Recombinant Monoclonal |
|
Isotype |
IgG |
|
Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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