Cytokeratin 8 Rabbit Monoclonal Antibody(ARA739)

Key features and details

  • Target: Cytokeratin 8
  • Clone ID: ARA739
  • Host: Rabbit
  • Clone Type: Recombinant Monoclonal
  • Purity: ProA affinity purified IgG
  • Species Cross-reactivity: Human
  • Applications: WB, IHC-P, IF/ICC, FC, IP
  • Isotype: IgG
  • Brand:
CAT.NO. : ARA6526
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Size:
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Product Details
Background
Cytokeratin 8 (CK8) is a member of the type II intermediate filament (IF) gene family, the majority of the cellular CK8 is assembled with its partner, CK18, into highly insoluble 10 nm filaments that extend from the nucleus to the internal leaflet of the plasma membrane.CK8 is always expressed by simple epithelial cells and by some carcinoma cells. In non-cancerous tissue, CK8 commonly expressed in normal glandular epithelia, transitional cell epithelium, and hepatocyte. In cancerous tissue, CK8 high expressed in adenocarcinoma, such as human breast or colorectal carcinoma.
Application

Application

Dilution Ratio

WB

1:2,500-1:5,000

IHC-P

1:100-1:200

IF/ICC

1:5,000-1:10,000

FC

1:200-1:800

IP

1:10-1:30

Overview

Host Species

Rabbit

Species Cross-reactivity

Human

Application

WB, IHC-P, IF/ICC, FC, IP

Immunogen

A synthetic peptide corresponding to residues on the C-terminus of human Cytokeratin 8 was used as an immunogen.

Purity

ProA affinity purified IgG

Clone Type

Recombinant Monoclonal

Isotype

IgG

Buffer

PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%

Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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