Cytokeratin 8 Rabbit Monoclonal Antibody(ARB855)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
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Brand:
CAT.NO. : ARB6645
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Size:
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Product Details
Background
Cytokeratin 8 (CK8) is a member of the type II intermediate filament (IF) gene family, the majority of the cellular CK8 is assembled with its partner, CK18, into highly insoluble 10 nm filaments that extend from the nucleus to the internal leaflet of the plasma membrane.CK8 is always expressed by simple epithelial cells and by some carcinoma cells. In non-cancerous tissue, CK8 commonly expressed in normal glandular epithelia, transitional cell epithelium, and hepatocyte. In cancerous tissue, CK8 high expressed in adenocarcinoma, such as human breast or colorectal carcinoma.
Overview
| Target | Cytokeratin 8 |
| Host Species | rabbit monoclonal antibody |
| Molecular Weight | 54 kDa |
| Purity | ProA affinity purified IgG |
| Species Cross-reactivity | Human |
| Form | Liquid |
| Applications | IHC-P |
| Swissprot ID | P05787 |
| Immunogen | Synthetic peptide corresponding to CK-8 residues within aa383-C terminal of CK-8 |
| Storage Buffer | PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
| Storage Conditions | -25°C to -18°C |
| Dilutions | IHC-P: 1:100-1:200 |
| Subcellular Location | Cytoplasm |
| Recommended Method | Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18° C-25°C) for 30 minutes |
Data
Immunohistochemical staining of human lung adenocarcinoma tissue sections using Cytokeratin 8 Rabbit Monoclonal Antibody (ARB855).
Immunohistochemical staining of human mammary gland tissue sections using Cytokeratin 8 Rabbit Monoclonal Antibody (ARB855).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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