DNP Rabbit Monoclonal Antibody(ARA904)

Key features and details

Reactivity:Human, Mouse, Rat, Monkey
Application:IHC
Host:Rabbit
Clonality:Monoclonal
Target:DNP

Brand:

CAT.NO. : ARA6739

RMB Please choose

Size:

1mL 100μL

Trail, Bulk size or Custom requests Please contact us

Product Details

Background

Ral A and Ral B constitute a distinct subfamily of Ras-related GTPases (i.e., GDP/GTP binding proteins). Ral proteins are activated by a unique nucleotide exchange factor, Ral GDS, and deactivated by a distinct GTPase-activating protein. Unlike Ras proteins, Ral A and Ral B fail to induce transformed foci when activated variants are expressed in various recipient cells. A potential downstream target of Ral, designated Ral BP-1, has been shown to contain a Rho-GTPase-activating domain. This Rho-GTPase-activating domain interacts preferentially with the Rho family member Cdc42. A Ras/Ral signaling pathway has been reported to mediate phospholipase D (PLD) activation by v-Src, thus indicating PLD as another downstream target of Ral A.

Application

Application	Dilution Ratio
IHC-P	1:50-1:200

Overview

Antibody Type	Recombinant Rabbit monoclonal Antibody
Immunogen	Recombinant protein within Human RALBP1 aa 205-300 / 655
Species Reactivity	Human, Mouse, Rat, Monkey
Validated Applications	WB, IHC-P, IF-Cell, FC
Molecular Weight	Predicted band size: 76 kDa
Positive Control	MCF7 cell lysate, COS-1 cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, C6 cell lysate, PC-12 cell lysate, human lung tissue, human pancreas tissue, mouse pancreas tissue, rat pancreas tissue, rat lung tissue, human breast carcinoma tissue, MCF7, NIH/3T3, C6
Conjugation	unconjugated
Form	Liquid
Concentration	1μg/μl
Storage Buffer	1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide
Isotype	IgG
Purification Method	Protein A affinity purified