DUSP4 Mouse Monoclonal Antibody(ARM615)
Key features and details
- Target:
- Clone ID:
- Host:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
- Storage:
-
Brand:
CAT.NO. : ARM6906
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Size:
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Product Details
Background
DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:50 - 1:200 |
Overview
|
Gene Name |
DUSP4 |
|
Application |
IHC |
|
Raised In |
Mouse |
|
Clonality |
Monoclonal |
|
Reactivity |
Human |
|
Immunogen |
Recombinant Protein |
|
Isotype |
IgG1 |
|
Uniprot Number |
Q13115 |
|
Storage Buffer |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Storage Condition |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing |
Data
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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