E-Cadherin Rabbit Monoclonal Antibody(ARA737)
Key features and details
- Target:
- Clone ID:
- Host:
- Clone Type:
- Purity:
- Species Cross-reactivity:
- Applications:
- Isotype:
-
Brand:
CAT.NO. : ARA6524
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
Product Details
Background
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Application
|
Application |
Dilution Ratio |
|
WB |
1:5,000-1:1 |
|
IHC-P |
1:25-1:5 |
Overview
|
Host Species |
Rabbit |
|
Species Cross-reactivity |
Human |
|
Application |
WB, IHC-P |
|
Immunogen |
A synthetic peptide corresponding to E-Cadherin residues within aa 600-700 of human E-Cadherin. |
|
Purity |
ProA affinity purified IgG |
|
Clone Type |
Recombinant Monoclonal |
|
Isotype |
IgG |
|
Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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