EBER/Ribosomal Protein L22 Rabbit Polyclonal Antibody
Key features and details
- Reactivity:Human, Mouse, Rat
- Application:WB, IHC-P,ELISA
- Host:Rabbit
- Clonality:Polyclonal
- lsotype:IgG
- Target:EBER
-
Brand:
CAT.NO. : ARA6796
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Size:
Trail, Bulk size or Custom requests Please contact us
Product Details
Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:50 - 1:100 |
Overview
|
Theoretical Molecular Weight |
15kDa |
|
Observed Molecular Weight |
15kDa |
|
Positive Samples |
293T, HeLa, U-87MG, HepG2, Jurkat |
|
Storage Buffer |
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3 |
|
Immunogen |
Recombinant protein (or fragment).This information is considered to be commercially sensitive |
|
Form |
Liquid |
|
Conjugation |
Unconjugated |
|
Cellular Localization |
cytoplasm, cytosol, cytosolic ribosome, extracellular exosome, focal adhesion, nucleus |
|
Purification Method |
Affinity purification |
|
Gene ID |
6146 |
|
SwissProt |
P35268 |
|
Synonyms |
EAP; L22; HBP15; HBP15/L22; 22 |
Data
Immunohistochemical staining of human heart tissue sections using EBER Rabbit Polyclonal Antibody.
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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