Ehrlichia / Rickettsiales ELISA kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 检测范围:
- 样品类型:
- 标准范围:
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Brand:
CAT.NO. : ARG83069
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Size:
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Product Details
概述
| 产品描述 | ARG83069 Ehrlichia / Rickettsiales ELISA kit is an enzyme immunoassay kit for the qualitative Ehrlichia in animals serum. |
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| 反应物种 | Dog |
| 应用 | ELISA |
| 靶点名称 | Ehrlichia / Rickettsiales |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 检测范围 | Cut - off |
| 样品类型 | serum |
| 标准范围 | Cut - off |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: less than 4% Inter-Assay CV: less than 6% |
| 別名 | Ehrlichia |
应用说明
| 检测时间 | ~2 hour |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 背景介绍 | Ehrlichia species are transmitted to the mammalian host during tick feeding, being inoculated along with the tick saliva. Once introduced into the dermis, E. chaffeensis and E. canis have selective tropisms for monocytes and macrophages, while E. ewingii targets neutrophils and occasional eosinophils. On blood smears, the bacteria can be visualized as morulae, which are microcolonies of Ehrlichia inside host cell vesicles. Unlike the Rickettsiales, Ehrlichia do not replicate in the cytoplasm. Following uptake of the bacteria into vesicles, phagocytes disseminate hematogenously to the major target organs: liver, lung, spleen, and, for E. chaffeensis, the central nervous system. Ehrlichiae directly compromise the killing ability of these cells by preventing superoxide radical production and phagolysosomal fusion. |
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