EMA Mouse Monoclonal Antibody(ARM917)
Key features and details
- Reactivity:Human
- Application:IHC
- Host:Mouse
- Clonality:Monoclonal
- lsotype:IgG2a
- Target Name:EMA
-
Brand:
CAT.NO. : ARM6707
RMB Please choose
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Product Details
Background
Epithelial Membrane Antigen (EMA) is a mucin glycoprotein expressed on apical epithelial cells. Anti - EMA positively stains normal and neoplastic cells including sweat glands, mammary epithelia, and squamous epithelia. Adrenal carcinoma, seminomas, paraganglioma, hepatocellular carcinoma, and embryonal carcinomas exhibit a negative stain. As Anti - EMA commonly reacts positively with meningioma, it is useful for differentiating this tumour from other intracranial neoplasms such as schwannomas.
Application
IHC: 1:50-1:200
Overview
|
Molecular Weight |
122,102 Da |
|
Chromosome Location |
Chromosome: 1; NC_000001.10 (155158300..155162706, complement). Location: 1q21 |
|
OMIM |
113720 |
|
3D Structure |
ModBase 3D Structure for P15941 |
|
Clonality |
Monoclonal |
|
Isotype |
IgG2a |
|
Host |
Mouse |
|
Species Reactivity |
Human |
|
Specificity |
EMA |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast sections labeling EMA with ARM917
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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