ESA Rabbit Monoclonal Antibody(ARA917)

Key features and details

Reactivity:Human, Mouse, Rat, Monkey
Application:IHC
Host:Rabbit
Clonality:Monoclonal
Target:ESA

Brand:

CAT.NO. : ARA6752

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Size:

1mL

Trail, Bulk size or Custom requests Please contact us

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Product Details

Background

Flotillin-2 is a protein that in humans is encoded by the FLOT2 gene. Flotillin 2 (flot-2) is a highly conserved protein isolated from caveolae/lipid raft domains that tether growth factor receptors linked to signal transduction pathways. Flot-2 binds to PAR-1, a known upstream mediator of major signal transduction pathways implicated in cell growth and metastasis, and may influence tumour progression. Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling.

Application

Application	Dilution Ratio
IHC-P	1:500-1:2000

Overview

Antibody Type	Recombinant Rabbit monoclonal Antibody
Immunogen	Recombinant protein within human Flotillin-2 aa 1-428 / 428
Species Reactivity	Human, Mouse, Rat, Monkey
Validated Applications	WB, IHC-P, IF-Cell, FC
Molecular Weight	Predicted band size: 47 kDa
Positive Control	HeLa cell lysate, A431 cell lysate, COS-1 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse lung tissue lysate, rat lung tissue lysate, HeLa, 293T cell lysate, A549 cell lysate, MCF7 cell lysate, human lung tissue lysate, mouse skin tissue lysate, rat skin tissue lysate, NIH/3T3, PC-12, human breast cancer tissue, human liver cancer tissue, mouse lung tissue, rat lung tissue
Conjugation	unconjugated
Form	Liquid
Concentration	1μg/μl
Storage Buffer	PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide
Isotype	IgG
Purification Method	Protein A affinity purified