Estrogen receptor beta Rabbit Monoclonal Antibody(ARB950)
Key features and details
- Target:
- Clone ID:
- Host:
- Molecular Weight:
- Purity:
- Species Cross-reactivity:
- Applications:
- Swissprot ID:
-
Brand:
CAT.NO. : ARB6742
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive system tissues.
ER-beta is expressed in tissues of the female reproductive system, such as ovaries and mammary glands.
The role of ER-beta in various cancer types is controversial, but it is generally thought to be a tumor suppressor. Absence of ER-beta has been shown to be a marker of poor prognosis in breast cancer.
ER-beta is expressed in tissues of the female reproductive system, such as ovaries and mammary glands.
The role of ER-beta in various cancer types is controversial, but it is generally thought to be a tumor suppressor. Absence of ER-beta has been shown to be a marker of poor prognosis in breast cancer.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:100 - 1:200 |
Overview
|
Predicted Molecular Wt |
59kDa |
|
Species Cross-reactivity |
Human |
|
Applications |
IHC-P |
|
Purity |
ProA affinity purified IgG |
|
Form |
Liquid |
|
Swissprot ID |
Q92731 |
|
Subcellular location |
Nucleus/Cytoplasmic |
|
Recommended Method |
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18℃-25℃) for 30 minutes |
|
Storage Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Data
Immunohistochemical staining of human breast tissue using Estrogen receptor beta Rabbit Monoclonal Antibody(ARB950)
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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