FAM171A2 Rabbit polyclonal Antibody
Key features and details
- Reactivity:Human
- Application:WB
- Host:Rabbit
- Clonality:polyclonal
- Target:FAM171A2
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Brand:
CAT.NO. : ARA6495
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Product Details
Background
FAM171A2 is a conserved protein‑coding gene across vertebrates. It encodes a transmembrane protein that is mainly expressed in neuronal cells. A key biological function of this gene is regulating the secretion of progranulin (PGRN), a glycoprotein linked to neurodevelopment and inflammatory responses. Moreover, FAM171A2 acts as a membrane receptor mediating the internalization and intercellular transmission of pathological α‑synuclein, making it closely associated with multiple neurodegenerative diseases such as Parkinson’s disease. Due to its critical roles in neural pathological processes, it has become a potential biomarker and therapeutic target for related neurodegenerative disorders.
Application
|
Application |
Dilution Ratio |
|
WB |
1/500 - 1/1000 |
Overview
| Item | Details |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FAM171A2. The exact sequence is proprietary. |
| Purification Method | The antibody was purified by immunogen affinity chromatography. |
| Clone Type | Polyclonal |
| Form | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
| Gene Name | FAM171A2 |
| Alias | Protein FAM171A2 |
| Gene ID (Human) | 284069 |
| Gene ID (Mouse) | 217219 |
| Protein ID (Human) | A8MVW0 |
| Protein ID (Mouse) | A2A699 |
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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