Fli-1 Rabbit Monoclonal Antibody(ARM617)
Key features and details
- Target:
- Clone ID:
- Host:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
-
Brand:
CAT.NO. : ARM6908
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Size:
Trail, Bulk size or Custom requests Please contact us
Product Details
Background
Friend Leukemia Integration 1 (Fli-1) is a transcription factor involved in cellular proliferation and tumourigenesis, and is normally expressed in endothelial and hematopoietic cells, including T-lymphocytes. Anti-Fli-1 is a valuable tool in the discrimination of Ewing’s sarcoma/peripheral primitive neuroectodermal tumour (ES/PNET) from most of its potential mimics. Most cases of ES/PNET are characterized by a chromosomal translocation resulting in a fusion oncoprotein and aberrant transcription factor EWS/Fli-1. Fli-1 has been found to play an important role in the embryologic development of blood vessels, and is specifically expressed in adult endothelial cells in all types of blood vessels, as well as in both benign and malignant vascular tumours.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Molecular Weight |
50,982 Da |
|
Chromosome Location |
Chromosome: 11; NC_000011.9 (128556430..128683162). Location: 11q24.1-q24.3 |
|
3D Structure |
ModBase 3D Structure for Q01543 |
|
Isotype |
IgG |
|
Host |
Rabbit |
|
Species Reactivity |
Human |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human colon tissue using Fli-1 Rabbit Monoclonal Antibody (ARM617).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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