Fumarase Activity Assay Kit (Colorimetric)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 靶点名称:
- 偶联标记说明:
- 灵敏度:
- 检测范围:
- 样品类型:
- 样本量:
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CAT.NO. : ARG82158
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Product Details
概述
| 产品描述 | ARG82158 Fumarase Activity Assay Kit (Colorimetric) can be used to measure Fumarase activity in serum, plasma, erythrocytes, tissue and cell culture supernatants. |
|---|---|
| 反应物种 | Hu, Ms, Rat, All |
| 应用 | FuncSt |
| 靶点名称 | Fumarase |
| 偶联标记说明 | Read at 565 nm |
| 灵敏度 | 0.4 U/L |
| 检测范围 | 0.4 - 70 U/L |
| 样品类型 | serum, plasma, erythrocytes, tissue and cell culture supernatants |
| 样本量 | 20 µl |
| 別名 | MCUL1; MCL; LRCC; EC 4.2.1.2; Fumarate hydratase, mitochondrial; FMRD; Fumarase; HLRCC |
应用说明
| 应用说明 | Please note that this kit does not include a microplate. |
|---|---|
| 检测时间 | 40 min |
属性
| 形式 | Liquid |
|---|---|
| 存放说明 | Store the kit at -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FH |
| 全名 | fumarate hydratase |
| 背景介绍 | The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008] |
| 生物功能 | Also acts as a tumor suppressor. [UniProt] |
| 细胞定位 | Isoform Mitochondrial: Mitochondrion. Isoform Cytoplasmic: Cytoplasm. [UniProt] |
| 产品亮点 | Related products: Fumarase antibodies; Fumarase ELISA Kits; Related news: TCA intermediate fumarate promotes mitobiogenesis |
检测图片 (1)
ARG82158 Fumarase Activity Assay Kit (Colorimetric) enzyme kinetics graph
Kinetics of 0 and 70 U/L Fumarase reaction, using ARG82158 Fumarase Activity Assay Kit (Colorimetric).
参考文献
Resolvin D1 reduces mitochondrial damage to photoreceptors of primary retinal cells exposed to high glucose.
FuncSt / Mouse
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