Glutathione S-transferase Activity Assay Kit (Colorimetric)
Key features and details
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- 反应物种:
- 应用:
- 靶点名称:
- 偶联标记说明:
- 灵敏度:
- 检测范围:
- 样品类型:
- 样本量:
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Brand:
CAT.NO. : ARG82167
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Product Details
概述
| 产品描述 | ARG82167 Glutathione S-transferase Activity Assay Kit (Colorimetric) can be used to measure Glutathione S-transferase activity in cell lysates and tissues. |
|---|---|
| 反应物种 | Hu, Ms, Rat, All |
| 应用 | FuncSt |
| 靶点名称 | Glutathione S-transferase |
| 偶联标记说明 | Read at 340 nm |
| 灵敏度 | 2 U/L |
| 检测范围 | 2 - 80 U/L |
| 样品类型 | cell lysates and tissues |
| 样本量 | 20 µl |
| 別名 | GST HB subunit 4; MU-1; GST class-mu 1; GST1; Glutathione S-transferase Mu 1; GSTM1-1; GSTM1a-1a; MU; GTH4; EC 2.5.1.18; GSTM1b-1b; H-B; GTM1 |
应用说明
| 应用说明 | Please note that this kit does not include a microplate. |
|---|---|
| 检测时间 | 10 min |
属性
| 形式 | Liquid |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GSTM1 |
| 全名 | glutathione S-transferase mu 1 |
| 背景介绍 | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
检测图片 (1)
ARG82167 Glutathione S-transferase Activity Assay Kit (Colorimetric) enzyme kinetics graph
Kinetics of 0 and 80 U/L Glutathione S-transferase reaction, using ARG82167 Glutathione S-transferase Activity Assay Kit (Colorimetric).
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