Glypican-3 Mouse Monoclonal Antibody(ARM500)
CAT.NO. : ARM6790
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Background
Glypican-3 (GPC3) is a GPI-anchored proteoglycan involved in cell division and growth regulation. Glypican-3 is a useful tumour marker, and its expression has been shown to be upregulated in hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumours, and Wilms’ tumour. Patients with HCC have presented elevated levels of GPC3 in the neoplastic liver tissues and serum, levels which are higher than detected in cirrhotic liver or liver with focal lesions, including those with hepatic adenoma and dysplastic nodules. Glypican-3 is also overexpressed in testicular germ cell tumours of certain subtypes, such as yolk sac tumours and choriocarcinoma, and in embryonal tumours.
Application
Application |
Dilution Ratio |
IHC |
1:100 - 1:500 |
Overview
Molecular Weight |
65,563 Da |
Chromosome Location |
Chromosome: X; NC_000023.10 (132669773..133119673, complement). Location: Xq26.1 |
3D Structure |
ModBase 3D Structure for P51654 |
Isotype |
IgG1 |
Host |
Mouse |
Species Reactivity |
Human |
Purity/Purification |
Purified |
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
Immunogen |
Recombinant Protein |
Data

Immunohistochemical staining of human liver tissue using Glypican-3 Mouse Monoclonal Antibody (ARM500).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
