Granzyme B Rabbit Monoclonal Antibody(ARA816)
CAT.NO. : ARA6606
RMB Please choose
RMB Please choose
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Background
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating.
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