Granzyme B Rabbit Monoclonal Antibody(ARA816)

Key features and details

  • Target: Granzyme B
  • Clone ID: ARA816
  • Host: Rabbit
  • Clone Type: Recombinant Monoclonal
  • Purity: ProA affinity purified IgG
  • Species Cross-reactivity: Human
  • Applications: IHC-P
  • Isotype: IgG
  • Brand:
CAT.NO. : ARA6606
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Product Details
Background
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating.
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