HDAC1 Rabbit Monoclonal Antibody(ARA781)
Key features and details
- Target:
- Clone ID:
- Host:
- Clone Type:
- Purity:
- Species Cross-reactivity:
- Applications:
- Isotype:
-
Brand:
CAT.NO. : ARA6568
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
Product Details
Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons.
Application
|
Application |
Dilution Ratio |
|
WB |
1:200-1:500 |
|
IHC-P |
1:50-1:200 |
|
IF/ICC |
1:1,000-1:2,000 |
|
FC |
1:100-1:200 |
Overview
|
Host Species |
Rabbit |
|
Species Cross-reactivity |
Human, Bovine, Green Monkey |
|
Application |
IF/ICC, FC, IHC-P |
|
Immunogen |
A synthetic peptide corresponding to the C-term of HDAC1 was used as an immunogen. |
|
Purity |
ProA affinity purified IgG |
|
Clone Type |
Recombinant Monoclonal |
|
Isotype |
IgG |
|
Buffer |
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05% |
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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