HNF-4-alpha Rabbit Monoclonal Antibody(ARA887)
Key features and details
- Reactivity:Human, Mouse, Rat
- Application:IHC
- Host:Rabbit
- Clonality:Monoclonal
- Target:HNF-4-alpha
-
Brand:
CAT.NO. : ARA6714
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
HNF-4 alpha is a transcription factor that binds DNA as a homodimer. HNF-4 alpha is important in liver, kidney, and intestinal development. It has also been intensely studied as one of a variety of genes responsible for diabetes mellitus. HNF-4 alpha has been shown in knock out mice to be essential for the morphogenic and functional differentiation of hepatocytes. HNF-4 alpha is a dominant regulator of epithelial phenotypes able to drive the mesenchymal-to-epithelial transition when expressed in fibroblasts.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:200-1:3000 |
Overview
|
Antibody Type |
Recombinant Rabbit monoclonal Antibody |
|
Immunogen |
Synthetic peptide within Human HNF-4-alpha aa 21-70 / 474 |
|
Species Reactivity |
Human, Mouse, Rat |
|
Validated Applications |
WB, IF-Cell, IHC-P, FC |
|
Molecular Weight |
Predicted band size: 53 kDa |
|
Positive Control |
A549 cell lysates, LOVO cell lysates, HepG2, SW480, human colon cancer tissue, human small intestine tissue, mouse colon tissue, rat colon tissue, Mouse liver tissue lysate, Mouse kidney tissue lysate, Mouse brain tissue lysate |
|
Conjugation |
unconjugated |
|
RRID |
AB_3070022 |
|
Form |
Liquid |
|
Concentration |
1μg/ul |
|
Storage Buffer |
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol, Preservative: 0.05% Sodium Azide |
|
Isotype |
IgG |
|
Purification Method |
Protein A affinity purified |
Data
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue with HNF-4-alpha Rabbit Monoclonal Antibody(ARA887)
Immunohistochemical analysis of paraffin-embedded human small intestine tissue with HNF-4-alpha Rabbit Monoclonal Antibody(ARA887)
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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