Hsp90 alpha ELISA kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
- 标准范围:
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Brand:
CAT.NO. : ARG81394
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Product Details
概述
| 产品描述 | ARG81394 Hsp90 alpha ELISA kit is an Enzyme Immunoassay kit for the quantification of Hsp90 alpha in serum, cell lysates and tissue lysates. |
|---|---|
| 反应物种 | Hu, Goat |
| 应用 | ELISA |
| 靶点名称 | Hsp90 alpha |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 0.117 ng/ml |
| 样品类型 | Serum, cell lysates and tissue lysates. |
| 标准范围 | 0.44 - 28 ng/ml |
| 样本量 | 100 µl |
| 別名 | EL52; Hsp90; HSPC1; Heat shock 86 kDa; LAP-2; HSP90N; LAP2; HSP90A; HSPCAL4; HSP89A; HSP86; HSP 86; HSPCA; Lipopolysaccharide-associated protein 2; HSPCAL1; LPS-associated protein 2; HSPN; Renal carcinoma antigen NY-REN-38; Heat shock protein HSP 90-alpha; Hsp89 |
应用说明
| 检测时间 | ~ 3 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HSP90AA1 |
| 全名 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| 背景介绍 | The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| 生物功能 | Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm. Melanosome. Cell membrane. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. [UniProt] |
| 产品亮点 | Related products: Hsp90 alpha antibodies; Hsp90 alpha ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | ISGylated. S-nitrosylated; negatively regulates the ATPase activity and the activation of eNOS by HSP90AA1. [UniProt] |
检测图片 (1)
ARG81394 Hsp90 alpha ELISA kit standard curve image
ARG81394 Hsp90 alpha ELISA kit results of a typical standard run with optical density reading at 450 nm.
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