Human Annexin A5 recombinant protein (His-tagged, C-ter)
Key features and details
- 产品描述:
- 应用:
- 靶点名称:
- 物种:
- A.A. 序列:
- 表达系统:
- Protein Full name:
- 別名:
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Brand:
CAT.NO. : ARG70472
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Product Details
概述
| 产品描述 | E. coli expressed, His-tagged (C-ter) Human Annexin A5 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | Annexin A5 |
| 物种 | Human |
| A.A. 序列 | Met1 - Asp320 |
| 表达系统 | E. coli |
| Protein Full name | Annexin A5 |
| 別名 | ANXA5; Annexin A5; CPB-I; PAP-I; Placental Anticoagulant Protein I; Vascular Anticoagulant-Alpha; Calphobindin I; Endonexin II; Annexin V; VAC-Alph; RPRGL3; ANX5 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | >98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | ANXA5 |
|---|---|
| 全名 | ANXA5 |
| 背景介绍 | The Annexin 5 gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. Polymorphisms in this gene have been implicated in various obstetric complications. |
| 生物功能 | This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. |
| 细胞定位 | Cytoplasm, cytosol, endothelial microparticle, external side of plasma membrane, extracellular exosome, extracellular region, focal adhesion, membrane |
| 翻译后修饰 | Acetylation, Isopeptide bond, Phosphoprotein, S-nitrosylation, Ubl conjugation |
检测图片 (1)
ARG70472 Human Annexin A5 recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70472 Human Annexin A5 recombinant protein (His-tagged, C-ter)
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