Human Apolipoprotein E ELISA Kit (Rapid One-Step)
Key features and details
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- 反应物种:
- 应用:
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- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
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Brand:
CAT.NO. : ARG83332
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Product Details
概述
| 产品描述 | Human Apolipoprotein E ELISA Kit (Rapid One-Step) is an Enzyme Immunoassay kit for the quantification of Human Apolipoprotein E in serum, plasma, saliva, urine, human milk and cell culture supernatants. It is a rapid One-step 90 minutes protocol. |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | Apolipoprotein E |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 60 pg/ml |
| 检测范围 | 3.12 ng/ml - 200 ng/ml |
| 样品类型 | Serum, plasma, saliva, urine, human milk and cell culture supernatants |
| 精确 | Intra-Assay CV: 6.8% Inter-Assay CV: 8.4% |
| 別名 | Apolipoprotein E; Apo-E; APO-E; LPG; AD2; LDLCQ5 |
应用说明
| 检测时间 | ~ 1.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | APOE |
| 全名 | apolipoprotein E |
| 背景介绍 | The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] |
| 生物功能 | Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. [UniProt] |
| 产品亮点 | Related products: Apolipoprotein antibodies; Apolipoprotein ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Synthesized with the sialic acid attached by O-glycosidic linkage and is subsequently desialylated in plasma. O-glycosylated with core 1 or possibly core 8 glycans. Thr-307 and Ser-314 are minor glycosylation sites compared to Ser-308. Glycated in plasma VLDL of normal subjects, and of hyperglycemic diabetic patients at a higher level (2-3 fold). Phosphorylated by FAM20C in the extracellular medium. |
检测图片 (1)
ARG83332 Human Apolipoprotein E ELISA Kit (Rapid One-Step) standard curve image
ARG83332 Human Apolipoprotein E ELISA Kit (Rapid One-Step)results of a typical standard run with optical density reading at 450 nm.
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