Human C1q / Complement 1q ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG82650
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Product Details
概述
| 产品描述 | ARG82650 Human C1q / Complement 1q ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human C1q / Complement 1q in serum, plasma, cell culture supernatants, urine, saliva, milk and CSF. |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Cross-Reactivity: Monkey: Dog: Mouse, Rat, Pig, Bovine and Rabbit: None No significant cross-reactivity observed with complement C1r, C1s, C2, C3, C4, C5, C6, C7, C8, C9, factor B, factor D, factor H, factor I and factor P. |
| 靶点名称 | C1q / Complement 1q |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 0.097 ng/ml |
| 样品类型 | Serum, plasma, cell culture supernatants, urine, saliva, milk and CSF. |
| 标准范围 | 0.156 - 10 ng/ml |
| 样本量 | 50 µl |
| 精确 | Intra-Assay CV: 5.2% Inter-Assay CV: 10.0% |
| 別名 | C1q / Complement 1q subcomponent subunit A |
应用说明
| 检测时间 | ~ 4 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store components at 4°C or -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P02745 Human Complement C1q subcomponent subunit A |
|---|---|
| 基因名称 | C1QA |
| 全名 | complement component 1, q subcomponent, A chain |
| 背景介绍 | This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016] |
| 生物功能 | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 产品亮点 | Related products: Complement component antibodies; Complement component ELISA Kits; Complement component Duos / Panels; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | O-linked glycans are assumed to be the Glc-Gal disaccharides typically found as secondary modifications of hydroxylated lysines in collagen-like domains. [UniProt] |
检测图片 (1)
ARG82650 Human C1q / Complement 1q ELISA Kit standard curve image
ARG82650 Human C1q / Complement 1q ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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