Human CASPR2 ELISA Kit
Key features and details
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- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 检测范围:
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Brand:
CAT.NO. : ARG83254
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Product Details
概述
| 产品描述 | ARG83254 Human CASPR2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CASPR2 in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | CASPR2 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 13 pg/ml |
| 检测范围 | 15.6 pg/ml - 1,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 6.3% Inter-Assay CV: 7.4% |
| 別名 | CNTNAP2; Contactin Associated Protein 2; KIAA0868; NRXN4; Contactin Associated Protein Like 2; Contactin-Associated Protein-Like 2; Cell Recognition Molecule Caspr2; Caspr2; CASPR2; Homolog Of Drosophila Neurexin IV; AUTS15; PTHSL1; CDFE |
应用说明
| 检测时间 | ~ 5 hours |
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属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9UHC6 Human Contactin-associated protein-like 2 |
|---|---|
| 基因名称 | CNTNAP2 |
| 全名 | Contactin Associated Protein 2 |
| 背景介绍 | This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and intellectual disability. |
| 生物功能 | Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction. |
| 细胞定位 | Cell junction, Cell projection, Membrane |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein |
检测图片 (1)
ARG83254 Human CASPR2 ELISA Kit standard curve image
ARG83254 Human CASPR2 ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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