Human Cathepsin C ELISA Kit

Key features and details

  • 产品描述: ARG83261 Human Cathepsin C ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Cathepsin C in Serum, Plasma and Cell culture supernatants.
  • 反应物种: Hu
  • 应用: ELISA
  • 特异性: There is no detectable cross-reactivity with other relevant proteins.
  • 靶点名称: Cathepsin C
  • 偶联标记: HRP
  • 偶联标记说明: Substrate: TMB and read at 450 nm.
  • 灵敏度: 100 pg/ml
  • 检测范围: 156 pg/ml - 10,000 pg/ml
  • Brand:
CAT.NO. : ARG83261
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Product Details
概述
产品描述ARG83261 Human Cathepsin C ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Cathepsin C in Serum, Plasma and Cell culture supernatants.
反应物种Hu
应用ELISA
特异性There is no detectable cross-reactivity with other relevant proteins.
靶点名称Cathepsin C
偶联标记HRP
偶联标记说明Substrate: TMB and read at 450 nm.
灵敏度100 pg/ml
检测范围156 pg/ml - 10,000 pg/ml
样品类型Serum, Plasma and Cell culture supernatants
精确Intra-Assay CV: 5.5%
Inter-Assay CV: 4.3%
別名CTSC; Cathepsin C; Dipeptidyl Peptidase 1; DPP1; Dipeptidyl Transferase; Cathepsin J; EC 3.4.14.1; DPP-I; CPPI; DPPI; PALS; PLS; Dipeptidyl-Peptidase I; Dipeptidyl Peptidase I; PDON1; HMS; JPD; JP
应用说明
检测时间~ 5 hours
属性
形式96 well
存放说明Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1075 Human CTSC

Swiss-port # P53634 Human Dipeptidyl peptidase 1

基因名称CTSC
全名Cathepsin C
背景介绍This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.
生物功能Activates serine proteases such as elastase, cathepsin G and granzymes A and B.
细胞定位Lysosome
翻译后修饰Disulfide bond, Glycoprotein, Zymogen
检测图片 (1)
  • ARG83261 Human Cathepsin C ELISA Kit standard curve image

    ARG83261 Human Cathepsin C ELISA Kitresults of a typical standard run with optical density reading at 450 nm.

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