Human CD262 / TRAIL-R2 ELISA Kit
Key features and details
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- 应用:
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- 靶点名称:
- 偶联标记:
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Brand:
CAT.NO. : ARG81332
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Product Details
概述
| 产品描述 | ARG81332 Human CD262 / TRAIL-R2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD262 / TRAIL-R2 in serum, plasma and cell culture supernatant. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Specific for Human CD262 / TRAIL-R2. No cross reactivity was observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R1, TRAIL R3, TRAIL R4, CD178 and Granzyme B. |
| 靶点名称 | CD262 / TRAIL R2 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 6 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 31.25 - 1000 pg/ml |
| 样本量 | 100 µl |
| 別名 | TRICK2A; TRICK2B; KILLER; TRAILR2; TNF-related apoptosis-inducing ligand receptor 2; DR5; CD antigen CD262; TRICK2; CD262; KILLER/DR5; Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; TRAIL-R2; TRAIL receptor 2; TRICKB; ZTNFR9 |
应用说明
| 检测时间 | ~ 2.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O14763 Human Tumor necrosis factor receptor superfamily member 10B |
|---|---|
| 基因名称 | TNFRSF10B |
| 全名 | tumor necrosis factor receptor superfamily, member 10b |
| 背景介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009] |
| 生物功能 | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. [UniProt] |
| 产品亮点 | Related products: CD262 antibodies; CD262 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
检测图片 (1)
ARG81332 Human CD262 / TRAIL-R2 ELISA Kit standard curve image
ARG81332 Human CD262 / TRAIL-R2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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