Human CD263 / TRAIL-R3 ELISA Kit
Key features and details
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- 靶点名称:
- 偶联标记:
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Brand:
CAT.NO. : ARG81333
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Product Details
概述
| 产品描述 | ARG81333 Human CD263 / TRAIL-R3 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD263 / TRAIL-R3 in serum, plasma and cell culture supernatant. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Specific for Human CD263 / TRAIL-R3. No cross reactivity was observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R1, TRAIL R2, TRAIL R4, CD178, and Granzyme B. |
| 靶点名称 | CD263 / TRAIL R3 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 147 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 312.5 - 10000 pg/ml |
| 样本量 | 100 µl |
| 別名 | Lymphocyte inhibitor of TRAIL; Antagonist decoy receptor for TRAIL/Apo-2L; TNF-related apoptosis-inducing ligand receptor 3; DCR1; TRID; CD antigen CD263; Tumor necrosis factor receptor superfamily member 10C; CD263; Decoy TRAIL receptor without death domain; LIT; Decoy receptor 1; DcR1; DCR1-TNFR; TRAIL-R3; TRAIL receptor 3; TRAILR3; TRAIL receptor without an intracellular domain |
应用说明
| 检测时间 | ~ 4 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O14798 Human Tumor necrosis factor receptor superfamily member 10C |
|---|---|
| 基因名称 | TNFRSF10C |
| 全名 | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| 背景介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. [UniProt] |
| 产品亮点 | Related products: CD263 antibodies; CD263 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | N-glycosylated and O-glycosylated. [UniProt] |
检测图片 (1)
ARG81333 Human CD263 / TRAIL-R3 ELISA Kit standard curve image
ARG81333 Human CD263 / TRAIL-R3 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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