Human CD31 ELISA Kit
Key features and details
- Specificity:10 pg/ml
- Detection Range: 156 pg/ml - 10000 pg/ml
- Sample Types: Cell Culture Supernates, Serum, Plasma
- Gene Name: PECAM1
- Species:Human
- Target:CD31
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Brand:
CAT.NO. : ARE6615
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Size:
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Product Details
Background
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
Overview
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Product Description |
Sandwich ELISA for quantitative detection of Human CD31 concentrations. |
|
Specificity |
10 pg/ml |
|
Gene Name |
PECAM1 |
|
Related Names |
Platelet endothelial cell adhesion molecule; PECAM - 1; EndoCAM; GPIIA; PECA1; CD31 |
|
Gene ID (Human) |
5175 |
|
Protein ID (Human) |
P16284 |
|
Detection Range |
156 pg/ml - 10000 pg/ml |
|
Sample Types |
Cell Culture Supernates, Serum, Plasma |
Data
Representative Standard Curve
Storage
Shipped and store at 4°C for 6 months, store at -20°C for one year. Avoid freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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