Human CD58 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 检测范围:
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Brand:
CAT.NO. : ARG83237
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Product Details
概述
| 产品描述 | ARG83237 Human CD58 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD58 in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | CD58 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 25 pg/ml |
| 检测范围 | 312 pg/ml - 20,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 3.8% Inter-Assay CV: 4.5% |
| 別名 | CD antigen CD58; LFA3; ag3; Lymphocyte function-associated antigen 3; Surface glycoprotein LFA-3; Ag3; LFA-3 |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P19256 Human Lymphocyte function-associated antigen 3 |
|---|---|
| 基因名称 | CD58 |
| 全名 | CD58 molecule |
| 背景介绍 | CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form; the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B. |
| 生物功能 | Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. [UniProt] |
| 研究领域 | Immune System antibody |
检测图片 (1)
ARG83237 Human CD58 ELISA Kit standard curve image
ARG83237 Human CD58 ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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