Human CD66a / CEACAM1 ELISA Kit
Key features and details
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- 靶点名称:
- 偶联标记:
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Brand:
CAT.NO. : ARG81564
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Product Details
内含物
| 货号 | 内含物名称 | 包装 | 温度 |
|---|---|---|---|
| ARG81564-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG81564-002 | Standard | 2 X 20 ng/vial | 4°C |
| ARG81564-003 | Standard/Sample diluent | 30 ml (Ready to use) | 4°C |
| ARG81564-004 | Antibody conjugate concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81564-005 | Antibody diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81564-006 | HRP-Streptavidin concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81564-007 | HRP-Streptavidin diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81564-008 | 25X Wash buffer | 20 ml | 4°C |
| ARG81564-009 | TMB substrate | 10 ml (Ready to use) | 4°C (Protect from light) |
| ARG81564-010 | STOP solution | 10 ml (Ready to use) | 4°C |
| ARG81564-011 | Plate sealer | 4 strips | Room temperature |
概述
| 产品描述 | ARG81564 Human CD66a / CEACAM1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD66a / CEACAM1 in serum, plasma (heparin, EDTA) and cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | CD66a / CEACAM1 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 156 pg/ml |
| 样品类型 | Serum, plasma (heparin, EDTA) and cell culture supernatants. |
| 标准范围 | 312 - 20000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: 5.7% Inter-Assay CV: 6.8% |
| 別名 | Carcinoembryonic antigen-related cell adhesion molecule 1; BGP-1; BGP1; Biliary glycoprotein 1; BGP; BGPI; CD antigen CD66a |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P13688 Human Carcinoembryonic antigen-related cell adhesion molecule 1 |
|---|---|
| 基因名称 | CEACAM1 |
| 全名 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| 背景介绍 | This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010] |
| 产品亮点 | Related products: CD66 antibodies; CD66 ELISA Kits; CD66 Duos / Panels; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Isoform 1: Phosphorylated on serine and tyrosine (By similarity). Isoform 1 is phosphorylated on tyrosine by Src family kinases like SRC and LCK and by receptor like CSF3R, EGFR and INSR upon stimulation (PubMed:15467833, PubMed:18424730, PubMed:7478590). Phosphorylated at Ser-508; mediates activity. Phosphorylated at Tyr-493; regulates activity (By similarity). Phosphorylated at Tyr-493 by EGFR and INSR upon stimulation; this phosphorylation is Ser-508-phosphorylation-dependent; mediates cellular internalization; increases interaction with downstream proteins like SHC1 and FASN (By similarity). Phosphorylated at Tyr-493 and Tyr-520 by LCK; mediates PTPN6 association and is regulated by homophilic ligation of CEACAM1 in the absence of T cell activation (PubMed:18424730). Phosphorylated at Tyr-520; mediates interaction with PTPN11 (By similarity). Isoform 8: Phosphorylated on serine and threonine. [UniProt] |
检测图片 (1)
ARG81564 Human CD66a / CEACAM1 ELISA Kit standard curve image
ARG81564 Human CD66a / CEACAM1 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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