Human CDNF recombinant protein (His-tagged, C-ter)
CAT.NO. : ARG70455
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概述
| 产品描述 | E. coli expressed, His-tagged (C-ter) Human CDNF recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | CDNF |
| 物种 | Human |
| A.A. 序列 | Gln27 - Leu187 |
| 表达系统 | E. coli |
| Protein Full name | Cerebral dopamine neurotrophic factor |
| 別名 | CDNF; Cerebral Dopamine Neurotrophic Factor; Conserved Dopamine Neurotrophic Factor; ARMETL1; Arginine-Rich, Mutated In Early Stage Tumors-Like 1; ARMET-Like Protein 1 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | >98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 8.0) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CDNF |
|---|---|
| 全名 | Cerebral Dopamine Neurotrophic Factor |
| 背景介绍 | Predicted to enable growth factor activity. Predicted to be involved in dopaminergic neuron differentiation and neuron projection development. Predicted to be active in endoplasmic reticulum and extracellular space. |
| 生物功能 | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). |
| 细胞定位 | Secreted |
| 翻译后修饰 | Disulfide bond |
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