Human CEACAM3 ELISA Kit
Key features and details
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- 反应物种:
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- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
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Brand:
CAT.NO. : ARG83248
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Product Details
概述
| 产品描述 | ARG83248 Human CEACAM3 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CEACAM3 in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | CEACAM3 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 13 pg/ml |
| 检测范围 | 15.6 pg/ml - 1,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 2.7% Inter-Assay CV: 4.2% |
| 別名 | CGM1; W282; Carcinoembryonic antigen CGM1; CEA; Carcinoembryonic antigen-related cell adhesion molecule 3; W264; CD66D; CD antigen CD66d |
应用说明
| 检测时间 | ~ 5 hours |
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属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P40198 Human Carcinoembryonic antigen-related cell adhesion molecule 3 |
|---|---|
| 基因名称 | CEACAM3 |
| 全名 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| 背景介绍 | This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013] |
| 生物功能 | Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis. [UniProt] |
| 细胞定位 | Membrane, Single-pass type I membrane protein. [UniProt] |
| 翻译后修饰 | Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected. [UniProt] |
检测图片 (1)
ARG83248 Human CEACAM3 ELISA Kit standard curve image
ARG83248 Human CEACAM3 ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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