Human CFHR1 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 检测范围:
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Brand:
CAT.NO. : ARG83250
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Product Details
概述
| 产品描述 | ARG83250 Human CFHR1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CFHR1 in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | CFHR1 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 25 pg/ml |
| 检测范围 | 312 pg/ml - 20,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 6.4% Inter-Assay CV: 5.9% |
| 別名 | CFHR1; Complement Factor H Related 1; FHR1; CFHL; CFHL1P; CFHR1P; H36-1; H36-2; CFHL1; HFL1; HFL2; Complement Factor H-Related 1 Pseudogene; Complement Factor H-Related Protein 1; H Factor (Complement)-Like 1; H Factor (Complement)-Like 2; H Factor-Like Protein 1; H-Factor-Like 1; FHL-1; FHR-1; H36; Complement Factor H-Related 1 |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q03591 Human Complement factor H-related protein 1 |
|---|---|
| 基因名称 | CFHR1 |
| 全名 | Complement Factor H Related 1 |
| 背景介绍 | This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. |
| 生物功能 | Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. |
| 细胞定位 | Secreted |
| 翻译后修饰 | Disulfide bond, Glycoprotein |
检测图片 (1)
ARG83250 Human CFHR1 ELISA Kit standard curve image
ARG83250 Human CFHR1 ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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