Human COLEC12 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 检测范围:
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Brand:
CAT.NO. : ARG83263
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Product Details
概述
| 产品描述 | ARG83263 Human COLEC12 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human COLEC12 in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | COLEC12 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 13 pg/ml |
| 检测范围 | 156 pg/ml - 10,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 5.0% Inter-Assay CV: 5.9% |
| 別名 | COLEC12; Collectin Subfamily Member 12; SCARA4; SRCL; CL-P1; Scavenger Receptor With C-Type Lectin; Nurse Cell Scavenger Receptor 2; Collectin Placenta Protein 1; Collectin-12; HCL-P1; CLP1; NSR2; Scavenger Receptor Class A, Member 4; Scavenger Receptor Class A Member 4; Collectin Sub-Family Member 12 |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | COLEC12 |
| 全名 | Collectin Subfamily Member 12 |
| 背景介绍 | This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells. |
| 生物功能 | Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid-beta in Alzheimer disease. |
| 细胞定位 | Membrane |
| 翻译后修饰 | Disulfide bond, Glycoprotein |
检测图片 (1)
ARG83263 Human COLEC12 ELISA Kit standard curve image
ARG83263 Human COLEC12 ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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