Human Complement C2 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 检测范围:
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Brand:
CAT.NO. : ARG83228
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Product Details
概述
| 产品描述 | ARG83228 Human Complement C2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Complement C2 in Serum, Plasma, Urine and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | Complement C2 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 25 pg/ml |
| 检测范围 | 312 pg/ml - 20,000 pg/ml |
| 样品类型 | Serum, Plasma, Urine and Cell culture supernatants |
| 精确 | Intra-Assay CV: 4.7% Inter-Assay CV: 3.7% |
| 別名 | C2; Complement C2; Complement Component 2; C3/C5 Convertase; EC 3.4.21.43; Complement Component C2; EC 3.4.21; ARMD14; CO2 |
应用说明
| 检测时间 | ~ 5 hours |
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属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | C2 |
| 全名 | Complement C2 |
| 背景介绍 | Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined. |
| 生物功能 | Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. |
| 细胞定位 | Secreted |
| 翻译后修饰 | Disulfide bond, Glycoprotein |
检测图片 (1)
ARG83228 Human Complement C2 ELISA Kit standard curve image
ARG83228 Human Complement C2 ELISA Kitresults of a typical standard run with optical density reading at 450 nm.
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