Human CXCL11 / I-TAC ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- Protein Full name:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG82966
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Product Details
概述
| 产品描述 | ARG82966 Human CXCL11 / I-TAC ELISA Kitis an Enzyme Immunoassay kit for the quantification of Human CXCL11 / I-TAC in serum, plasma and cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | CXCL11 / I-TAC |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| Protein Full name | C-X-C motif chemokine 11 |
| 灵敏度 | 3.9 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 7.8 - 500 pg/ml |
| 样本量 | 100 μl |
| 精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| 別名 | SCYB9B; SCYB11; C-X-C motif chemokine 11; Beta-R1; b-R1; Interferon gamma-inducible protein 9; I-TAC; Small-inducible cytokine B11; Interferon-inducible T-cell alpha chemoattractant; H174; IP-9; IP9 |
应用说明
| 检测时间 | ~ 3.5 hours |
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属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CXCL11 |
| 全名 | chemokine (C-X-C motif) ligand 11 |
| 背景介绍 | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014] |
| 生物功能 | Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. [UniProt] |
| 产品亮点 | Related products: CXCL11 antibodies; CXCL11 ELISA Kits; Related news: circNDUFB2, a circular RNA (circRNA), activates anti-tumor immunity New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
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