Human CXCL2 / MIP2 ELISA Kit

Key features and details

  • 产品描述: ARG80185 Human CXCL2 / MIP2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CXCL2 / MIP2 in Serum, Plasma, Cell culture supernatants.
  • 反应物种: Hu
  • 应用: ELISA
  • 特异性: No significant cross-reactivity or interference with Human CXCL1, CXCL3, CXCL4, IL-2,3,4,5,6,7,9,10,12, IFN gamma and TNF alpha.
  • 靶点名称: CXCL2 / MIP2
  • 偶联标记: HRP
  • 偶联标记说明: Substrate: TMB and read at 450 nm
  • 灵敏度: 0.8 pg/ml
  • 样品类型: Serum, Plasma, Cell culture supernatants
  • Brand:
CAT.NO. : ARG80185
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Product Details
内含物
货号内含物名称包装温度
ARG80185-001Antibody-coated microplate8 X 12 strips 4°C. Unused strips should be sealed tightly in the air-tight pouch.
ARG80185-002Standard (Lyophilized)3 X 1 ng/vial 4°C
ARG80185-003Standard diluent buffer20 ml 4°C
ARG80185-004Antibody conjugate concentrate400 µl 4°C
ARG80185-005Antibody diluent buffer16 ml 4°C
ARG80185-006HRP-Streptavidin concentrate400 µl 4°C (Protect from light)
ARG80185-007HRP-Streptavidin diluent buffer16 ml 4°C
ARG80185-00820X Wash buffer50 ml 4°C
ARG80185-009TMB substrate12ml 4°C (Protect from light)
ARG80185-010STOP solution12ml 4°C
ARG80185-011Plate sealer4 strips Room temperature
概述
产品描述ARG80185 Human CXCL2 / MIP2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CXCL2 / MIP2 in Serum, Plasma, Cell culture supernatants.
反应物种Hu
应用ELISA
特异性No significant cross-reactivity or interference with Human CXCL1, CXCL3, CXCL4, IL-2,3,4,5,6,7,9,10,12, IFN gamma and TNF alpha.
靶点名称CXCL2 / MIP2
偶联标记HRP
偶联标记说明Substrate: TMB and read at 450 nm
灵敏度0.8 pg/ml
样品类型Serum, Plasma, Cell culture supernatants
标准范围1.56 - 100 pg/ml
样本量100 µl
精确Intra-Assay CV: less than10%; Inter-Assay CV: less than10%
別名Gro-beta; SCYB2; HSF; CINC-2a; GROb; MGSA-b; SB-251353; MIP2A; MIP2; Hematopoietic synergistic factor; 5-73; C-X-C motif chemokine 2; MIP-2a; GRO2; Macrophage inflammatory protein 2-alpha; GRO-beta-T; Growth-regulated protein beta; MIP2-alpha
应用说明
检测时间4 hours
属性
形式96 well
存放说明Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2920 Human CXCL2

Swiss-port # P19875 Human C-X-C motif chemokine 2

基因名称CXCL2
全名chemokine (C-X-C motif) ligand 2
背景介绍Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines. CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.
产品亮点Related products:
GRO beta antibodies; GRO beta ELISA Kits;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
研究领域Immune System kit
翻译后修饰The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
检测图片 (1)
  • ARG80185 Human CXCL2 / MIP2ELISA Kit standard curve image

    ARG80185 Human CXCL2 / MIP2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.

参考文献

Tumor cells educate mesenchymal stromal cells to release chemoprotective and immunomodulatory factors.

ELISA / Human / Cell culture supernatant

Augustin Le Naour et al.
J Mol Cell Biol.,  (2020)

publication_link

 

hr_line

Mesenchymal stromal cells release CXCL1/2/8 and induce chemoresistance and macrophage polarization.

ELISA / Human

Augustin Le Naour et al.
Preprint.,  (2018)

publication_link

 

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