Human FGF17 recombinant protein (Active) (His-tagged, N-ter)
Key features and details
- 产品描述:
- 应用:
- 靶点名称:
- 物种:
- A.A. 序列:
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- 活性说明:
- 別名:
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Brand:
CAT.NO. : ARG70123
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Product Details
概述
| 产品描述 | E. coli expressed, His-tagged (N-ter) Active Human FGF17 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | FGF17 |
| 物种 | Human |
| A.A. 序列 | Thr23 - Thr216 |
| 表达系统 | E. coli |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to induce 3T3 cells proliferation. The ED50 for this effect is2 x 10^5 IU/mg. |
| 別名 | FGF-17; HH20; FGF-13; Fibroblast growth factor 17 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | >98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 8.0) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | FGF17 |
|---|---|
| 全名 | fibroblast growth factor 17 |
| 背景介绍 | This gene encodes a member of the fibroblast growth factor (FGF) family. Member of the FGF family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is expressed during embryogenesis and in the adult cerebellum and cortex and may be essential for vascular growth and normal brain development. Mutations in this gene are the cause of hypogonadotropic hypogonadism 20 with or without anosmia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| 生物功能 | Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
检测图片 (1)
ARG70123 Human FGF17 recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70123 Human FGF17 recombinant protein (Active) (His-tagged, N-ter).
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